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Mouse Anti-PYGB Recombinant Antibody (CBYC-P807) (CBMAB-P3574-YC)

Provided herein is a Mouse monoclonal antibody against Human Glycogen Phosphorylase, Muscle Associated. The antibody can be used for immunoassay techniques, such as ELISA, IHC.
See all PYGB antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYC-P807
Antibody Isotype
IgG1
Application
ELISA, IHC

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Glycogen Phosphorylase, Muscle Associated
Introduction
PYGB (Glycogen Phosphorylase B) is a protein coding gene. Diseases associated with PYGB include Myocardial Infarction. Among its related pathways are Galactose metabolismand Regulation of lipid metabolism Insulin signaling-generic cascades. Gene Ontology annotations related to this gene include pyridoxal phosphate binding and glycogen phosphorylase activity. An important paralog of the gene is PYGM.
Entrez Gene ID
5834
UniProt ID
P11216
Alternative Names
GPBB; Glycogen Phosphorylase, Brain Form
Function
Glycogen phosphorylase that regulates glycogen mobilization (PubMed:27402852).
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism (PubMed:3346228).
Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates (PubMed:3346228).
However, all known phosphorylases share catalytic and structural properties (PubMed:3346228).
Biological Process
Glycogen catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
azurophil granule lumen
cytoplasm
extracellular exosome
extracellular region
membrane
PTM
Phosphorylated (PubMed:27402852).
Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A (By similarity).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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