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Mouse Anti-QRICH2 Recombinant Antibody (CBLG1-3242) (CBMAB-G6519-LY)

This product is antibody recognizes QRICH2. The antibody CBLG1-3242 immunoassay techniques such as: WB.
See all QRICH2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBLG1-3242
Antibody Isotype
IgG
Application
WB

Basic Information

Specificity
Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Glutamine Rich 2
Entrez Gene ID
84074
UniProt ID
Q9H0J4
Alternative Names
Glutamine Rich 2;
Function
Has an essential role in the formation of sperm flagella and flagellar structure maintainance. It acts as a suppressor of ubiquitination and degradation of proteins involved in flagellar development and motility.
Biological Process
Biological Process cell projection assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process flagellated sperm motilityManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process negative regulation of ubiquitin-dependent protein catabolic processManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Nucleus membrane
Nucleus
Cytoplasm
Cell projection, cilium, flagellum
Localization varies during spermatozoa development. The protein is distributed in the nuclear membrane of the spermatogonia, in the nucleus of round spermatids, in the nucleus and cytoplasm of early elongating spermatids, in the cytoplasm of late elongating spermatids, and in the flagella of epididymal spermatozoa.
Involvement in disease
Spermatogenic failure 35 (SPGF35):
An autosomal recessive infertility disorder caused by spermatogenesis defects that result in multiple abnormalities of sperm flagellum and severely impaired spermatozoa motility.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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