Mouse Anti-RAB11FIP5 Recombinant Antibody (3A8) (CBMAB-R0703-CN)

Name: Mouse Anti-RAB11FIP5 Recombinant Antibody (3A8)
SKU: CBMAB-R0703-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

3A8

Application

ELISA, WB

Immunogen

Partial recombinant protein corresponding to aa. 554-652 from human RAB11FIP5 (NP_056285) with GST tag

Specificity

Human

Antibody Isotype

IgG2b, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.4

More Infomation

Target

Full Name

RAB11 family interacting protein 5 (class I)

Introduction

RAB11FIP5 (RAB11 Family Interacting Protein 5) is a Protein Coding gene. Diseases associated with RAB11FIP5 include Neonatal Lupus Erythematosus and Atypical Autism. Among its related pathways are Endocytosis and Delta508-CFTR traffic / ER-to-Golgi in CF. Gene Ontology (GO) annotations related to this gene include Rab GTPase binding and gamma-tubulin binding. An important paralog of this gene is RAB11FIP1.

Entrez Gene ID

26056

UniProt ID

Q9BXF6

Alternative Names

RAB11 Family Interacting Protein 5; RAB11 Family Interacting Protein 5 (Class I); Rab11-Interacting Protein Rip11; Gamma-SNAP-Associated Factor 1; Phosphoprotein Pp75; Rab11-FIP5; Gaf-1;

Function

Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to extracellular acidosis.

Biological Process

Biological Process cellular response to acidic pHManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process insulin secretion involved in cellular response to glucose stimulusISS:UniProtKB
Biological Process negative regulation of adiponectin secretionManual Assertion Based On ExperimentIDA:CACAO
Biological Process regulated exocytosisISS:UniProtKB
Biological Process regulation of protein localization to cell surfaceManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Cytoplasm
Recycling endosome membrane
Early endosome membrane
Golgi apparatus membrane
Cytoplasmic vesicle, secretory vesicle membrane
Mitochondrion membrane

PTM

Phosphorylated on serine and threonine residues. Phosphorylation at Ser-357 is PKA-dependent.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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