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Mouse Anti-RAB11FIP5 Recombinant Antibody (3A8) (CBMAB-R0703-CN)

This product is a Mouse antibody that recognizes RAB11FIP5. The antibody 3A8 can be used for immunoassay techniques such as: ELISA, WB.
See all RAB11FIP5 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
3A8
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant protein corresponding to aa. 554-652 from human RAB11FIP5 (NP_056285) with GST tag
Specificity
Human
Antibody Isotype
IgG2b, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4

Target

Full Name
RAB11 family interacting protein 5 (class I)
Introduction
RAB11FIP5 (RAB11 Family Interacting Protein 5) is a Protein Coding gene. Diseases associated with RAB11FIP5 include Neonatal Lupus Erythematosus and Atypical Autism. Among its related pathways are Endocytosis and Delta508-CFTR traffic / ER-to-Golgi in CF. Gene Ontology (GO) annotations related to this gene include Rab GTPase binding and gamma-tubulin binding. An important paralog of this gene is RAB11FIP1.
Entrez Gene ID
26056
UniProt ID
Q9BXF6
Alternative Names
RAB11 Family Interacting Protein 5; RAB11 Family Interacting Protein 5 (Class I); Rab11-Interacting Protein Rip11; Gamma-SNAP-Associated Factor 1; Phosphoprotein Pp75; Rab11-FIP5; Gaf-1;
Function
Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to extracellular acidosis.
Biological Process
Biological Process cellular response to acidic pHManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process insulin secretion involved in cellular response to glucose stimulusISS:UniProtKB
Biological Process negative regulation of adiponectin secretionManual Assertion Based On ExperimentIDA:CACAO
Biological Process regulated exocytosisISS:UniProtKB
Biological Process regulation of protein localization to cell surfaceManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cytoplasm
Recycling endosome membrane
Early endosome membrane
Golgi apparatus membrane
Cytoplasmic vesicle, secretory vesicle membrane
Mitochondrion membrane
PTM
Phosphorylated on serine and threonine residues. Phosphorylation at Ser-357 is PKA-dependent.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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