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Mouse Anti-RAB2B Recombinant Antibody (7E4) (CBMAB-R0803-CN)

This product is a Mouse antibody that recognizes RAB2B. The antibody 7E4 can be used for immunoassay techniques such as: ELISA, WB.
See all RAB2B antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
7E4
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa. 127-217 from human RAB2B (NP_116235) with GST tag
Specificity
Human, Mouse
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
RAB2B, member RAS oncogene family
Introduction
Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508. [supplied by OMIM, Apr 2006]
Entrez Gene ID
Human84932
Mouse76338
UniProt ID
HumanQ8WUD1
MouseP59279
Alternative Names
RAB2B, Member RAS Oncogene Family;
Function
The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between active GTP-bound and inactive GDP-bound states. In their active state, drive transport of vesicular carriers from donor organelles to acceptor organelles to regulate the membrane traffic that maintains organelle identity and morphology. Regulates the compacted morphology of the Golgi (Probable). Promotes cytosolic DNA-induced innate immune responses. Regulates IFN responses against DNA viruses by regulating the CGAS-STING signaling axis (By similarity).
Biological Process
Biological Process defense response to virusISS:UniProtKB
Biological Process Golgi organizationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process innate immune responseISS:UniProtKB
Biological Process positive regulation of exocytosisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of type I interferon productionISS:UniProtKB
Biological Process protein transportIEA:UniProtKB-KW
Biological Process vesicle-mediated transportManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell membrane
Endoplasmic reticulum membrane
Golgi apparatus membrane
Cytoplasmic vesicle, secretory vesicle, acrosome
Localized in the Golgi apparatus in the round spermatids and in the acrosome in the elongating spermatid.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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