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Mouse Anti-RAB5B Recombinant Antibody (1615CT668.28.45) (CBMAB-R0919-CN)

This product is a Mouse antibody that recognizes RAB5B. The antibody 1615CT668.28.45 can be used for immunoassay techniques such as: WB.
See all RAB5B antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
1615CT668.28.45
Antibody Isotype
IgG1, κ
Application
WB

Basic Information

Immunogen
A recombinant protein of human RAB5B
Specificity
Human, Mouse
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
RAB5B, Member RAS Oncogene Family
Introduction
RAB5B (RAB5B, Member RAS Oncogene Family) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Innate Immune System. Gene Ontology (GO) annotations related to this gene include GTP binding and GDP binding. An important paralog of this gene is RAB5C.
Entrez Gene ID
Human5869
Mouse19344
UniProt ID
HumanP61020
MouseP61021
Alternative Names
RAB5B, Member RAS Oncogene Family;
Function
Protein transport. Probably involved in vesicular traffic.
Biological Process
Biological Process antigen processing and presentationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process endocytosisManual Assertion Based On ExperimentIBA:GO_Central
Biological Process endosome organizationIEA:Ensembl
Biological Process intracellular protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process plasma membrane to endosome transportManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process regulation of endocytosisManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell membrane
Early endosome membrane
Melanosome
Enriched in stage I melanosomes.
PTM
Phosphorylation of Ser-84 in the switch II region by LRRK2 prevents the association of RAB regulatory proteins, including CHM, CHML and RAB GDP dissociation inhibitors GDI1 and GDI2.
(Microbial infection) Glycosylated on arginine residues by S.typhimurium protein Ssek3.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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