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Mouse Anti-RAB9A Recombinant Antibody (Rab9-29) (CBMAB-R0957-CN)

This product is a Mouse antibody that recognizes RAB9A. The antibody Rab9-29 can be used for immunoassay techniques such as: WB, IP, ELISA, ICC.
See all RAB9A antibodies
Published Data
Fig.1 Rab9 binds specifically to the PH domain of SKIP, a protein that influences LAMP1 distribution in cells.
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Fig.2 RNAi-treated HeLa cells were fixed, permeabilized, and stained with anti-LAMP1 antibody (white).
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Fig.3 Immunostaining of the Rab9 transgene in the brain of NPCmut/mut animals at 7 weeks.
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Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Hamster, Dog, Human
Clone
Rab9-29
Antibody Isotype
IgG1
Application
WB, IP, ELISA, ICC

Basic Information

Specificity
Mouse, Rat, Hamster, Dog, Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
2.3 mg/mL

Target

Full Name
RAB9A, Member RAS Oncogene Family
Introduction
RAB9A (RAB9A, Member RAS Oncogene Family) is a Protein Coding gene. Among its related pathways are wtCFTR and deltaF508 traffic / Late endosome and Lysosome (norm and CF) and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include GTP binding and GDP binding. An important paralog of this gene is RAB9B.
Entrez Gene ID
Human9367
Mouse56382
Rat84589
Hamster100767493
Dog403947
UniProt ID
HumanP51151
MouseQ9R0M6
RatQ99P75
HamsterG3I185
DogP24408
Alternative Names
RAB9A, Member RAS Oncogene Family; RAB9, Member RAS Oncogene Family; RAB9; Ras-Related Protein Rab-9A;
Function
Involved in the transport of proteins between the endosomes and the trans Golgi network. Involved in the recruitment of SGSM2 to melanosomes and is required for the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes.
Biological Process
Biological Process negative regulation by host of symbiont catalytic activityManual Assertion Based On ExperimentIMP:AgBase
Biological Process positive regulation of exocytosisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein transportIEA:UniProtKB-KW
Biological Process Rab protein signal transductionIEA:InterPro
Biological Process regulation of protein localizationManual Assertion Based On ExperimentIMP:AgBase
Biological Process retrograde transport, endosome to GolgiManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell membrane
Endoplasmic reticulum membrane
Golgi apparatus membrane
Late endosome
Cytoplasmic vesicle, phagosome membrane
Cytoplasmic vesicle, phagosome
Cytoplasmic vesicle membrane
Melanosome
Colocalizes with OSBPL1A at the late endosome (PubMed:16176980).
Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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