RAB9A
RAB9A (RAB9A, Member RAS Oncogene Family) is a Protein Coding gene. Among its related pathways are wtCFTR and deltaF508 traffic / Late endosome and Lysosome (norm and CF) and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include GTP binding and GDP binding. An important paralog of this gene is RAB9B.
Full Name
RAB9A, Member RAS Oncogene Family
Function
Involved in the transport of proteins between the endosomes and the trans Golgi network. Involved in the recruitment of SGSM2 to melanosomes and is required for the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes.
Biological Process
Biological Process negative regulation by host of symbiont catalytic activityManual Assertion Based On ExperimentIMP:AgBase
Biological Process positive regulation of exocytosisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein transportIEA:UniProtKB-KW
Biological Process Rab protein signal transductionIEA:InterPro
Biological Process regulation of protein localizationManual Assertion Based On ExperimentIMP:AgBase
Biological Process retrograde transport, endosome to GolgiManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of exocytosisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein transportIEA:UniProtKB-KW
Biological Process Rab protein signal transductionIEA:InterPro
Biological Process regulation of protein localizationManual Assertion Based On ExperimentIMP:AgBase
Biological Process retrograde transport, endosome to GolgiManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell membrane
Endoplasmic reticulum membrane
Golgi apparatus membrane
Late endosome
Cytoplasmic vesicle, phagosome membrane
Cytoplasmic vesicle, phagosome
Cytoplasmic vesicle membrane
Melanosome
Colocalizes with OSBPL1A at the late endosome (PubMed:16176980).
Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211).
Endoplasmic reticulum membrane
Golgi apparatus membrane
Late endosome
Cytoplasmic vesicle, phagosome membrane
Cytoplasmic vesicle, phagosome
Cytoplasmic vesicle membrane
Melanosome
Colocalizes with OSBPL1A at the late endosome (PubMed:16176980).
Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211).
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Anti-RAB9A antibodies
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Target: RAB9A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBAb208
Application*: WB, IF
Target: RAB9A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse, Rat, Hamster, Dog, Human
Clone: Rab9-29
Application*: WB, IP, E, ICC
Target: RAB9A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey
Clone: D52G8
Application*: WB, IP, IF
Target: RAB9A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey
Clone: D22A6
Application*: WB, IP
Target: RAB9A
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBCNR-078
Application*: E, WB
Target: RAB9A
Host: Rabbit
Specificity: Human, Mouse, Rat
Clone: CBCNR-077
Application*: WB, IF
Target: RAB9A
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBCNR-076
Application*: WB, IF
Target: RAB9A
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBCNR-075
Application*: WB, E, IF
Target: RAB9A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Cattle, Dog, Hamster, Human, Monkey, Rat
Clone: 6D717
Application*: ICC, IH, IP, WB
Target: RAB9A
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1E12
Application*: E, IF, WB
Target: RAB9A
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse, Rat, Hamster, Cattle, Dog, Human
Clone: Mab9
Application*: WB, P, F
Target: RAB9A
Specificity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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