RAB9A

RAB9A (RAB9A, Member RAS Oncogene Family) is a Protein Coding gene. Among its related pathways are wtCFTR and deltaF508 traffic / Late endosome and Lysosome (norm and CF) and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include GTP binding and GDP binding. An important paralog of this gene is RAB9B.

RAB9A, Member RAS Oncogene Family

Involved in the transport of proteins between the endosomes and the trans Golgi network. Involved in the recruitment of SGSM2 to melanosomes and is required for the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes.

Biological Process negative regulation by host of symbiont catalytic activityManual Assertion Based On ExperimentIMP:AgBase
Biological Process positive regulation of exocytosisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process protein transportIEA:UniProtKB-KW
Biological Process Rab protein signal transductionIEA:InterPro
Biological Process regulation of protein localizationManual Assertion Based On ExperimentIMP:AgBase
Biological Process retrograde transport, endosome to GolgiManual Assertion Based On ExperimentIBA:GO_Central

Cell membrane
Endoplasmic reticulum membrane
Golgi apparatus membrane
Late endosome
Cytoplasmic vesicle, phagosome membrane
Cytoplasmic vesicle, phagosome
Cytoplasmic vesicle membrane
Melanosome
Colocalizes with OSBPL1A at the late endosome (PubMed:16176980).
Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211).