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Mouse Anti-RABGGTB Recombinant Antibody (1C2) (CBMAB-R0974-CN)

This product is a Mouse antibody that recognizes RABGGTB. The antibody 1C2 can be used for immunoassay techniques such as: ELISA, WB.
See all RABGGTB antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1C2
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
Full length recombinant corresponding to human RABGGTB, aa. 1-332 (H20790) with GST tag
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
Rab geranylgeranyltransferase, beta subunit
Introduction
This gene encodes the beta-subunit of the enzyme Rab geranylgeranyl-transferase (RabGGTase), which belongs to the protein prenyltransferase family. RabGGTase catalyzes the post-translational addition of geranylgeranyl groups to C-terminal cysteine residues of Rab GTPases. Three small nucleolar RNA genes are present in the intronic regions of this gene. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 3. [provided by RefSeq, Jan 2013]
Entrez Gene ID
5876
UniProt ID
P53611
Alternative Names
Rab Geranylgeranyltransferase Beta Subunit; Type II Protein Geranyl-Geranyltransferase Subunit Beta; Rab GG Transferase Beta; Rab GGTase Beta; GGTase-II-Beta; EC 2.5.1.60;
Function
Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A.
Biological Process
Biological Process protein geranylgeranylationISS:UniProtKB
Biological Process protein modification process1 PublicationNAS:UniProtKB
Biological Process protein prenylationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process visual perceptionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
cytosol
plasma membrane
Rab-protein geranylgeranyltransferase complex
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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