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Mouse Anti-RAD54B Recombinant Antibody (4A7) (CBMAB-R1140-CN)

This product is a Mouse antibody that recognizes RAD54B. The antibody 4A7 can be used for immunoassay techniques such as: ELISA, IF, WB.
See all RAD54B antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
4A7
Antibody Isotype
IgG1, κ
Application
ELISA, IF, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa. 801-910 from RAD54B (H01965) with GST tag
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
RAD54 Homolog B (S. Cerevisiae)
Introduction
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. [provided by RefSeq, Jul 2008]
Entrez Gene ID
25788
UniProt ID
Q9Y620
Alternative Names
RAD54 Homolog B (S. Cerevisiae); DNA Repair And Recombination Protein RAD54B; RAD54 Homolog B; EC 3.6.4.-; EC 3.6.1; RDH54;
Function
Involved in DNA repair and mitotic recombination. May play an active role in recombination processes in concert with other members of the RAD52 epistasis group.
Biological Process
Biological Process determination of adult lifespanIEA:Ensembl
Biological Process double-strand break repair via homologous recombinationManual Assertion Based On ExperimentIDA:MGI
Biological Process mitotic recombinationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process reciprocal meiotic recombinationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process response to ionizing radiationIEA:Ensembl
Biological Process response to xenobiotic stimulusIEA:Ensembl
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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