Rat Anti-RAE1 Recombinant Antibody (186107) (CBMAB-R0070-CN)

Name: Rat Anti-RAE1 Recombinant Antibody (186107)
SKU: CBMAB-R0070-CN
Rating: 5 (1 reviews)

See all RAE1 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Rat

Clone

186107

Application

Immunogen

Recombinant protein corresponding to aa. 29-227 from mouse Rae-1, NS0-derived (UniProt # Q9JI58)

Specificity

Mouse

Antibody Isotype

IgG2a

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, 0.5% BSA

Preservative

0.09% Sodium azide

More Infomation

Target

Full Name

RIBONUCLEIC ACID EXPORT 1

Introduction

Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Entrez Gene ID

66679

UniProt ID

Q8C570

Alternative Names

Ribonucleic Acid Export 1; Rae1 Protein Homolog; MRNP41; Homolog Of Yeast Rae1 (Bharathi) MRNA-Associated Protein Of 41 KDa (Kraemer); RAE1 (RNA Export 1, S.Pombe) Homolog; RAE1 RNA Export 1 Homolog (S. Pombe); MRNA-Associated Protein MRNP 41; MRNA-Associated Protein Mrnp 41; MRNA-Binding Protein, 41-KD;

Function

Acts as mRNA export factor involved in nucleocytoplasmic transport (PubMed:33849972, PubMed:20498086).
Plays a role in mitotic bipolar spindle formation (PubMed:17172455).
May function in attaching cytoplasmic mRNPs to the cytoskeleton both directly or indirectly (PubMed:17172455).

Biological Process

Biological Process cell cycleIEA:UniProtKB-KW
Biological Process cell divisionIEA:UniProtKB-KW
Biological Process cellular response to organic cyclic compoundIEA:Ensembl
Biological Process mRNA export from nucleusManual Assertion Based On ExperimentTAS:ProtInc
Biological Process nucleocytoplasmic transport1 PublicationIC:ComplexPortal
Biological Process regulation of mitotic spindle organizationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process RNA export from nucleusManual Assertion Based On ExperimentIBA:GO_Central
Biological Process transcription-dependent tethering of RNA polymerase II gene DNA at nuclear peripheryManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Cytoplasm
Nucleus
Cytoplasm, cytoskeleton, spindle pole
Nucleus envelope
Recruited from interphase nuclei to spindle MTs during mitosis.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Rat Anti-RAE1 Recombinant Antibody (186107)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Rat Anti-RAE1 Recombinant Antibody (199205) (CAT#: CBMAB-R0071-CN)

Rat Anti-RAE1 Recombinant Antibody (RM0511-14R4) (CAT#: CBMAB-R1156-CN)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry