Mouse Anti-RALB Recombinant Antibody (CBT4462) (V2LY-0625-LY586)
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Basic Information
| Application | Note |
| WB | 1:500-1:2,000 |
| FC | 1:200-1:400 |
| ELISA | 1:10,000 |
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles (By similarity).
Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells (By similarity).
Required for suppression of apoptosis (PubMed:17875936).
In late stages of cytokinesis, upon completion of the bridge formation between dividing cells, mediates exocyst recruitment to the midbody to drive abscission (PubMed:18756269).
Involved in ligand-dependent receptor mediated endocytosis of the EGF and insulin receptors (PubMed:10393179).
Biological Process cell cycleIEA:UniProtKB-KW
Biological Process cell divisionIEA:UniProtKB-KW
Biological Process cellular response to exogenous dsRNAManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process cellular response to starvationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of protein bindingManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of autophagosome assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of protein bindingManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of protein phosphorylationManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process positive regulation of protein serine/threonine kinase activityManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of exocyst assemblyISS:UniProtKB
Biological Process regulation of exocyst localizationISS:UniProtKB
Biological Process signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Midbody
During late cytokinesis, enriched at the midbody.
The farnesylated form confers resistance to the proapoptotic and anti-anchorage-dependent growth effects of geranylgeranyltransferase I inhibitors, including GGTI-2417.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols
Antibody Pairs
RALB Matched Antibody Pair (965) (CAT#: APMAB-965LY)
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Rat Anti-RALB Recombinant Antibody (399417) (CAT#: CBMAB-R1222-CN)
RALB Matched Antibody Pair (965) (CAT#: APMAB-965LY)
Mouse Anti-RALB Recombinant Antibody (CBCNR-161) (CAT#: CBMAB-R1227-CN)
Mouse Anti-RALB Recombinant Antibody (4D1) (CAT#: CBMAB-R1223-CN)
Mouse Anti-RALB Recombinant Antibody (CBT2312) (CAT#: V2LY-0625-LY585)
Mouse Anti-RALB Recombinant Antibody (CBCNR-163) (CAT#: CBMAB-R1229-CN)
Mouse Anti-RALB Recombinant Antibody (2C4) (CAT#: CBMAB-R1221-CN)
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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