Mouse Anti-RASGEF1A Recombinant Antibody (3D11) (CBMAB-R1491-CN)

Name: Mouse Anti-RASGEF1A Recombinant Antibody (3D11)
SKU: CBMAB-R1491-CN
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

3D11

Application

ICC, IP, WB

Immunogen

Recombinant human RanGEF

Specificity

Human, Mouse, Rat

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

More Infomation

Target

Full Name

RasGEF Domain Family Member 1A

Introduction

RASGEF1A (RasGEF Domain Family Member 1A) is a Protein Coding gene. Diseases associated with RASGEF1A include Intrahepatic Cholangiocarcinoma and Cholangiocarcinoma. Among its related pathways are RET signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include guanyl-nucleotide exchange factor activity and Ras guanyl-nucleotide exchange factor activity. An important paralog of this gene is RASGEF1B.

Entrez Gene ID

Human	221002
Mouse	70727
Rat	312664

UniProt ID

Human	Q8N9B8
Mouse	Q80ZJ1
Rat	D3ZZV7

Alternative Names

RasGEF Domain Family Member 1A; Ras-GEF Domain-Containing Family Member 1A; CG4853 Gene Product; CG4853;

Function

Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, KRAS, HRAS, and NRAS (in vitro). Plays a role in cell migration.

Biological Process

Biological Process cell migrationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of Ras protein signal transductionManual Assertion Based On ExperimentIDA:FlyBase
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

cytosol
plasma membrane

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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