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Mouse Anti-RASGEF1A Recombinant Antibody (3D11) (CBMAB-R1491-CN)

This product is a Mouse antibody that recognizes RASGEF1A. The antibody 3D11 can be used for immunoassay techniques such as: ICC, IP, WB.
See all RASGEF1A antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
3D11
Application
ICC, IP, WB

Basic Information

Immunogen
Recombinant human RanGEF
Specificity
Human, Mouse, Rat
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
RasGEF Domain Family Member 1A
Introduction
RASGEF1A (RasGEF Domain Family Member 1A) is a Protein Coding gene. Diseases associated with RASGEF1A include Intrahepatic Cholangiocarcinoma and Cholangiocarcinoma. Among its related pathways are RET signaling and Cytokine Signaling in Immune system. Gene Ontology (GO) annotations related to this gene include guanyl-nucleotide exchange factor activity and Ras guanyl-nucleotide exchange factor activity. An important paralog of this gene is RASGEF1B.
Entrez Gene ID
Human221002
Mouse70727
Rat312664
UniProt ID
HumanQ8N9B8
MouseQ80ZJ1
RatD3ZZV7
Alternative Names
RasGEF Domain Family Member 1A; Ras-GEF Domain-Containing Family Member 1A; CG4853 Gene Product; CG4853;
Function
Guanine nucleotide exchange factor (GEF) with specificity for RAP2A, KRAS, HRAS, and NRAS (in vitro). Plays a role in cell migration.
Biological Process
Biological Process cell migrationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of Ras protein signal transductionManual Assertion Based On ExperimentIDA:FlyBase
Biological Process Ras protein signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
cytosol
plasma membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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