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Mouse Anti-RASSF2 Recombinant Antibody (1509CT269.10.9.29) (CBMAB-R1538-CN)

This product is a Mouse antibody that recognizes RASSF2. The antibody 1509CT269.10.9.29 can be used for immunoassay techniques such as: WB.
See all RASSF2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1509CT269.10.9.29
Antibody Isotype
IgG2a
Application
WB

Basic Information

Immunogen
A recombinant protein between aa. 1-326 from human RASSF2
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
Ras Association Domain Family Member 2
Introduction
This gene encodes a protein that contains a Ras association domain. Similar to its cattle and sheep counterparts, this gene is located near the prion gene. Two alternatively spliced transcripts encoding the same isoform have been reported. [provided by RefSeq, Jul 2008]
Entrez Gene ID
9770
UniProt ID
P50749
Alternative Names
Ras Association Domain Family Member 2; Ras Association (RalGDS/AF-6) Domain Family Member 2; Centromere Protein 34; CENP-34; Ras Association (RalGDS/AF-6) Domain Family 2; Ras Association Domain-Containing Protein 2; RASFADIN; KIAA0168;
Function
Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
Biological Process
Biological Process bone remodelingIEA:Ensembl
Biological Process cell cycleIEA:UniProtKB-KW
Biological Process epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascadeIEA:Ensembl
Biological Process homeostasis of number of cellsIEA:Ensembl
Biological Process negative regulation of NIK/NF-kappaB signalingIEA:Ensembl
Biological Process negative regulation of peptidyl-serine phosphorylationManual Assertion Based On ExperimentIDA:MGI
Biological Process ossificationIEA:Ensembl
Biological Process positive regulation of apoptotic processManual Assertion Based On ExperimentIDA:MGI
Biological Process positive regulation of JNK cascadeManual Assertion Based On ExperimentIDA:MGI
Biological Process positive regulation of protein autophosphorylationManual Assertion Based On ExperimentIDA:MGI
Biological Process positive regulation of protein kinase activityManual Assertion Based On ExperimentIDA:MGI
Biological Process protein stabilizationManual Assertion Based On ExperimentIMP:BHF-UCL
Biological Process regulation of NIK/NF-kappaB signalingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of osteoblast differentiationIEA:Ensembl
Biological Process regulation of osteoclast differentiationIEA:Ensembl
Biological Process signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process skeletal system developmentIEA:Ensembl
Cellular Location
Nucleus
Cytoplasm
Chromosome, centromere, kinetochore
Translocates to the cytoplasm in the presence of STK3/MST2 AND STK4/MST1.
PTM
Phosphorylated by STK3/MST2 and STK4/MST1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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