Mouse Anti-RDH10 Recombinant Antibody (F-6) (CBMAB-R1976-CN)

Name: Mouse Anti-RDH10 Recombinant Antibody (F-6)
SKU: CBMAB-R1976-CN
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

F-6

Application

WB, IP, IF, ELISA

Specificity

Mouse, Rat, Human

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

More Infomation

Target

Full Name

Retinol Dehydrogenase 10

Introduction

This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. [provided by RefSeq, Dec 2011]

Entrez Gene ID

Human	157506
Mouse	98711
Rat	353252

UniProt ID

Human	Q8IZV5
Mouse	Q8VCH7
Rat	Q80ZF7

Alternative Names

Retinol Dehydrogenase 10; Short Chain Dehydrogenase/Reductase Family 16C Member 4; Retinol Dehydrogenase 10 (All-Trans); SDR16C4; Short Chain Dehydrogenase/Reductase Family 16C, Member 4; EC 1.1.1.300; EC 1.1.1.n2; EC 1.1.1;

Function

Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol.

Biological Process

Biological Process bud elongation involved in lung branchingIEA:Ensembl
Biological Process ear developmentIEA:Ensembl
Biological Process embryonic camera-type eye developmentIEA:Ensembl
Biological Process embryonic forelimb morphogenesisIEA:Ensembl
Biological Process embryonic viscerocranium morphogenesisIEA:Ensembl
Biological Process gonad developmentIEA:Ensembl
Biological Process in utero embryonic developmentIEA:Ensembl
Biological Process metanephros developmentIEA:Ensembl
Biological Process neural crest cell developmentIEA:Ensembl
Biological Process nose developmentIEA:Ensembl
Biological Process positive regulation of retinoic acid biosynthetic processIEA:Ensembl
Biological Process primary lung bud formationIEA:Ensembl
Biological Process retinal metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process retinoic acid biosynthetic processIEA:Ensembl
Biological Process retinoid metabolic processTAS:Reactome
Biological Process retinol metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process visual perceptionManual Assertion Based On ExperimentIDA:MGI

Cellular Location

Microsome membrane
Endoplasmic reticulum membrane

Topology

Helical: 3-23

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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