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Mouse Anti-RDH10 Recombinant Antibody (F-6) (CBMAB-R1976-CN)

This product is a Mouse antibody that recognizes RDH10. The antibody F-6 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all RDH10 antibodies

Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
F-6
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse, Rat, Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
Retinol Dehydrogenase 10
Introduction
This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. [provided by RefSeq, Dec 2011]
Entrez Gene ID
Human157506
Mouse98711
Rat353252
UniProt ID
HumanQ8IZV5
MouseQ8VCH7
RatQ80ZF7
Alternative Names
Retinol Dehydrogenase 10; Short Chain Dehydrogenase/Reductase Family 16C Member 4; Retinol Dehydrogenase 10 (All-Trans); SDR16C4; Short Chain Dehydrogenase/Reductase Family 16C, Member 4; EC 1.1.1.300; EC 1.1.1.n2; EC 1.1.1;
Function
Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol.
Biological Process
Biological Process bud elongation involved in lung branchingIEA:Ensembl
Biological Process ear developmentIEA:Ensembl
Biological Process embryonic camera-type eye developmentIEA:Ensembl
Biological Process embryonic forelimb morphogenesisIEA:Ensembl
Biological Process embryonic viscerocranium morphogenesisIEA:Ensembl
Biological Process gonad developmentIEA:Ensembl
Biological Process in utero embryonic developmentIEA:Ensembl
Biological Process metanephros developmentIEA:Ensembl
Biological Process neural crest cell developmentIEA:Ensembl
Biological Process nose developmentIEA:Ensembl
Biological Process positive regulation of retinoic acid biosynthetic processIEA:Ensembl
Biological Process primary lung bud formationIEA:Ensembl
Biological Process retinal metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process retinoic acid biosynthetic processIEA:Ensembl
Biological Process retinoid metabolic processTAS:Reactome
Biological Process retinol metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process visual perceptionManual Assertion Based On ExperimentIDA:MGI
Cellular Location
Microsome membrane
Endoplasmic reticulum membrane
Topology
Helical: 3-23
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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