Mouse Anti-RECQL Recombinant Antibody (4D5) (CBMAB-R2014-CN)

Name: Mouse Anti-RECQL Recombinant Antibody (4D5)
SKU: CBMAB-R2014-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

4D5

Application

ELISA, WB

Immunogen

Partial recombinant corresponding to aa. 549-649, from human RECQL (NP_116559) with GST tag

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

More Infomation

Target

Full Name

RecQ Like Helicase

Introduction

The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. The encoded protein is involved in the processing of Holliday junctions, the suppression of sister chromatid exchanges, telomere maintenance, and is required for genotoxic stress resistance. Defects in this gene have been associated with several types of cancer. [provided by RefSeq, Jan 2017]

Entrez Gene ID

5965

UniProt ID

P46063

Alternative Names

RecQ Like Helicase; RecQ Protein-Like (DNA Helicase Q1-Like); DNA Helicase, RecQ-Like Type 1; DNA-Dependent ATPase Q1; RecQ Protein-Like 1; RecQ Helicase-Like; RECQL1;

Function

DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction.

Biological Process

Biological Process DNA duplex unwindingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process DNA recombinationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process DNA repairManual Assertion Based On ExperimentIBA:GO_Central
Biological Process DNA unwinding involved in DNA replicationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process double-strand break repair via homologous recombinationManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Antibody Pairs

RECQL Matched Antibody Pair (980) (CAT#: APMAB-980LY)

Related Products

RECQL Matched Antibody Pair (980) (CAT#: APMAB-980LY)

Mouse Anti-RECQL Recombinant Antibody (Q1N3) (CAT#: CBMAB-R2017-CN)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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