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Mouse Anti-RECQL Recombinant Antibody (Q1N3) (CBMAB-R2017-CN)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
Q1N3
Antibody Isotype
IgG1
Application
WB, IF

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
RecQ Like Helicase
Introduction
The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. The encoded protein is involved in the processing of Holliday junctions, the suppression of sister chromatid exchanges, telomere maintenance, and is required for genotoxic stress resistance. Defects in this gene have been associated with several types of cancer. [provided by RefSeq, Jan 2017]
Entrez Gene ID
5965
UniProt ID
P46063
Alternative Names
RecQ Like Helicase; RecQ Protein-Like (DNA Helicase Q1-Like); DNA Helicase, RecQ-Like Type 1; DNA-Dependent ATPase Q1; RecQ Protein-Like 1; RecQ Helicase-Like; RECQL1;
Function
DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction.
Biological Process
Biological Process DNA duplex unwindingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process DNA recombinationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process DNA repairManual Assertion Based On ExperimentIBA:GO_Central
Biological Process DNA unwinding involved in DNA replicationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process double-strand break repair via homologous recombinationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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