Mouse Anti-RETN Recombinant Antibody (CBCNR-417) (CBMAB-R2261-CN)

Name: Mouse Anti-RETN Recombinant Antibody (CBCNR-417)
SKU: CBMAB-R2261-CN
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

CBCNR-417

Application

ELISA, IHC-P, WB

Immunogen

E.coli derived recombinant Human Resistin

Specificity

Human

Antibody Isotype

IgG2b, κ

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

LYOPH

Buffer

PBS

More Infomation

Target

Full Name

Resistin

Introduction

This gene belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]

Entrez Gene ID

56729

UniProt ID

Q9HD89

Alternative Names

Resistin; C/EBP-Epsilon-Regulated Myeloid-Specific Secreted Cysteine-Rich Protein; Cysteine-Rich Secreted Protein A12-Alpha-Like 2; Adipose Tissue-Specific Secretory Factor; Cysteine-Rich Secreted Protein FIZZ3; FIZZ3; ADSF; RSTN;

Function

Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells (By similarity).
Potentially links obesity to diabetes (By similarity).
Promotes chemotaxis in myeloid cells (PubMed:15064728).

Biological Process

Biological Process agingIEA:Ensembl
Biological Process fat cell differentiationIEA:Ensembl
Biological Process negative regulation of feeding behaviorIEA:Ensembl
Biological Process positive regulation of progesterone secretionIEA:Ensembl
Biological Process positive regulation of synaptic transmissionIEA:Ensembl
Biological Process response to insulinIEA:Ensembl
Biological Process response to mechanical stimulusIEA:Ensembl

Cellular Location

Secreted

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Antibody Pairs

RETN Matched Antibody Pair (986) (CAT#: APMAB-986LY)

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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