Sign in or Register   Sign in or Register
  |  

Mouse anti-RGS1 Recombinant Antibody (CBMAB-1323-LY)

This product is antibody recognizes RGS1. The antibody immunoassay techniques such as: ELISA.
See all RGS1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Antibody Isotype
IgG
Application
WB, ICC, IHC-P, IHC-F, ELISA

Basic Information

Immunogen
Regulator Of G Protein Signaling 1
Specificity
Human
Antibody Isotype
IgG
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% glycerol
Preservative
0.02% NaN3
Concentration
0.5 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Regulator Of G Protein Signaling 1
Introduction
This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the N-formylpeptide chemoattractant receptors and leukotriene receptors
Entrez Gene ID
5996
UniProt ID
Q08116
Alternative Names
1R20; BL34; IER1; IR20; HEL-S-87
Function
Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the N-formylpeptide chemoattractant receptors and leukotriene receptors (PubMed:10480894).
Inhibits B cell chemotaxis toward CXCL12 (By similarity).
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form (PubMed:10480894, PubMed:18434541).
Biological Process
Biological Process adenylate cyclase-inhibiting G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Biological Process G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process immune responseManual Assertion Based On ExperimentTAS:ProtInc
Biological Process leukotriene signaling pathwayManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process negative regulation of signal transductionIEA:UniProtKB-KW
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of G protein-coupled receptor signaling pathwayIEA:InterPro
Biological Process response to bacteriumIEA:Ensembl
Biological Process signal transductionManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cell membrane
Cytoplasm, cytosol
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse anti-RGS1 Recombinant Antibody?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Documents

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Go to
Compare