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Mouse Anti-RGS16 Recombinant Antibody (1D3) (CBMAB-R2436-CN)

This product is a Mouse antibody that recognizes RGS16. The antibody 1D3 can be used for immunoassay techniques such as: WB, IHC, IF.
See all RGS16 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1D3
Antibody Isotype
IgG1
Application
WB, IHC, IF

Basic Information

Immunogen
Full length human recombinant protein of human RGS16 (NP_002919) produced in HEK293T cell
Specificity
Human
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.3, 1% BSA, 50% Glycerol
Preservative
0.02% Sodium azide
Concentration
0.88 mg/mL

Target

Full Name
Regulator Of G Protein Signaling 16
Introduction
The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008]
Entrez Gene ID
6004
UniProt ID
O15492
Alternative Names
Regulator Of G Protein Signaling 16; Retinally Abundant Regulator Of G-Protein Signaling; Regulator Of G-Protein Signalling 16; Regulator Of G-Protein Signaling 16; Retinal-Specific RGS; A28-RGS14P;
Function
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11602604, PubMed:18434541).
Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals (By similarity).
Biological Process
Biological Process G protein-coupled receptor signaling pathwayISS:UniProtKB
Biological Process negative regulation of signal transductionIEA:UniProtKB-KW
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Biological Process visual perceptionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Membrane
PTM
Palmitoylated on Cys-2 and/or Cys-12.
Phosphorylated. Phosphorylation at Tyr-168 by EGFR enhances GTPase accelerating (GAP) activity toward GNAI1.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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