RGS16

The protein encoded by this gene belongs to the 'regulator of G protein signaling' family. It inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. [provided by RefSeq, Jul 2008]
Full Name
Regulator Of G Protein Signaling 16
Function
Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:11602604, PubMed:18434541).
Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals (By similarity).
Biological Process
Biological Process G protein-coupled receptor signaling pathwayISS:UniProtKB
Biological Process negative regulation of signal transductionIEA:UniProtKB-KW
Biological Process positive regulation of GTPase activityManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Biological Process visual perceptionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Membrane
PTM
Palmitoylated on Cys-2 and/or Cys-12.
Phosphorylated. Phosphorylation at Tyr-168 by EGFR enhances GTPase accelerating (GAP) activity toward GNAI1.
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Anti-RGS16 antibodies

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Mouse Anti-RGS16 Recombinant Antibody (4F9) (CBMAB-R2444-CN)

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Target: RGS16
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4F9
Application*: WB, IH
Datasheet SDS

Mouse Anti-RGS16 Recombinant Antibody (4E5) (CBMAB-R2443-CN)

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Target: RGS16
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse, Human
Clone: 4E5
Application*: WB, P, F, IF
Datasheet SDS

Mouse Anti-RGS16 Recombinant Antibody (4C9) (CBMAB-R2442-CN)

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Target: RGS16
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 4C9
Application*: WB, P, IF
Datasheet SDS

Mouse Anti-RGS16 Recombinant Antibody (3F3) (CBMAB-R2441-CN)

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Target: RGS16
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3F3
Application*: IF, IH, WB
Datasheet SDS

Mouse Anti-RGS16 Recombinant Antibody (3B4) (CBMAB-R2440-CN)

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Target: RGS16
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 3B4
Application*: IH, WB
Datasheet SDS

Mouse Anti-RGS16 Recombinant Antibody (2C9) (CBMAB-R2439-CN)

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Target: RGS16
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2C9
Application*: WB, IF
Datasheet SDS

Mouse Anti-RGS16 Recombinant Antibody (1H7) (CBMAB-R2438-CN)

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Target: RGS16
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1H7
Application*: F, WB
Datasheet SDS

Mouse Anti-RGS16 Recombinant Antibody (1F3) (CBMAB-R2437-CN)

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Target: RGS16
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1F3
Application*: IH, WB
Datasheet SDS

Mouse Anti-RGS16 Recombinant Antibody (1D3) (CBMAB-R2436-CN)

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Target: RGS16
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1D3
Application*: WB, IH, IF
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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