Mouse Anti-RHOF Recombinant Antibody (1D4B6) (CBMAB-R0293-CN)

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Basic Information

Host Animal
Mouse
Clone
1D4B6
Application
WB, FC
Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
1 mg/mL
More Infomation

Target

Full Name
Ras Homolog Family Member F, Filopodia Associated
Introduction
RHOF (Ras Homolog Family Member F, Filopodia Associated) is a Protein Coding gene. Diseases associated with RHOF include Charcot-Marie-Tooth Disease, Axonal, Type 2L and Malaria. Among its related pathways are Innate Immune System and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is RHOD.
Entrez Gene ID
UniProt ID
Alternative Names
Ras Homolog Family Member F, Filopodia Associated; Rho In Filopodia; Ras Homolog Gene Family, Member F (In Filopodia); Ras Homolog Family Member F (In Filopodia); Rho Family GTPase Rif; ARHF; RIF; Rho-Related GTP-Binding Protein RhoF;
Function
Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Causes the formation of thin, actin-rich surface projections called filopodia. Functions cooperatively with CDC42 and Rac to generate additional structures, increasing the diversity of actin-based morphology.
Biological Process
Biological Process actin filament organizationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cortical cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process establishment or maintenance of cell polarityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of actin cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of cell shapeManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of small GTPase mediated signal transductionTAS:Reactome
Biological Process small GTPase mediated signal transductionIEA:InterPro
Cellular Location
Cell membrane
Cytoplasm, cytoskeleton
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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