Mouse Anti-RIMS2 Recombinant Antibody (CBCNR-505) (CBMAB-R2669-CN)

Name: Mouse Anti-RIMS2 Recombinant Antibody (CBCNR-505)
SKU: CBMAB-R2669-CN
Rating: 5 (1 reviews)

See all RIMS2 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBCNR-505

Application

WB, IP

Specificity

Human, Rat

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration

> 1 mg/mL

More Infomation

Target

Full Name

Regulating Synaptic Membrane Exocytosis 2

Introduction

The protein encoded by this gene is a presynaptic protein that interacts with RAB3, a protein important for normal neurotransmitter release. The encoded protein can also bind several other synaptic proteins, including UNC-13 homolog B, ELKS/Rab6-interacting/CAST family member 1, and synaptotagmin 1. This protein is involved in synaptic membrane exocytosis. Polymorphisms in this gene have been associated with degenerative lumbar scoliosis. [provided by RefSeq, Feb 2017]

Entrez Gene ID

Human	9699
Rat	116838

UniProt ID

Human	Q9UQ26
Rat	Q9JIS1

Alternative Names

Regulating Synaptic Membrane Exocytosis 2; Rab-3-Interacting Molecule 2; Rab-3-Interacting Protein 3; RAB3 Interacting Protein 3; RAB3IP3; RIM2; Regulating Synaptic Membrane Exocytosis Protein 2; Non-Small Cell Lung Cancer RimL3a Protein;

Function

Rab effector involved in exocytosis. May act as scaffold protein. Plays a role in dendrite formation by melanocytes (PubMed:23999003).

Biological Process

Biological Process adenylate cyclase-modulating G protein-coupled receptor signaling pathwayISS:ParkinsonsUK-UCL
Biological Process calcium ion-regulated exocytosis of neurotransmitterISS:ParkinsonsUK-UCL
Biological Process calcium-ion regulated exocytosisISS:ParkinsonsUK-UCL
Biological Process cell differentiationIEA:UniProtKB-KW
Biological Process insulin secretionISS:ParkinsonsUK-UCL
Biological Process intracellular protein transportIEA:InterPro
Biological Process positive regulation of dendrite extensionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of excitatory postsynaptic potentialISS:ParkinsonsUK-UCL
Biological Process positive regulation of inhibitory postsynaptic potentialISS:ParkinsonsUK-UCL
Biological Process positive regulation of synaptic transmissionManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of exocytosisISS:ParkinsonsUK-UCL
Biological Process regulation of membrane potentialISS:ParkinsonsUK-UCL
Biological Process regulation of synaptic plasticityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process spontaneous neurotransmitter secretionISS:ParkinsonsUK-UCL

Cellular Location

Cell membrane
Synapse
Presynaptic cell membrane

Involvement in disease

Cone-rod synaptic disorder syndrome, congenital non-progressive (CRSDS):
An autosomal recessive disorder characterized by reduced visual acuity, photophobia, nystagmus, distinctive electroretinographic features, neurodevelopmental delay, poor or absent language, autistic behaviors, and abnormal glucose homeostasis.

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-RIMS2 Recombinant Antibody (CBCNR-505)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-RIMS2 Recombinant Antibody (3C12) (CAT#: CBMAB-R2667-CN)

Mouse Anti-RIMS2 Recombinant Antibody (CBCNR-504) (CAT#: CBMAB-R2668-CN)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry