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Rat Anti-RIOX2 (AA 300-465) Recombinant Antibody (CBFYM-3086) (CBMAB-M3282-FY)

This product is rat antibody that recognizes RIOX2. The antibody CBFYM-3086 can be used for immunoassay techniques such as: WB, IF.
See all RIOX2 antibodies

Summary

Host Animal
Rat
Specificity
Human
Clone
CBFYM-3086
Antibody Isotype
IgG2a, k
Application
WB, IF

Basic Information

Immunogen
Partial recombinant protein (300-465 aa) expressed in E. coli
Specificity
Human
Antibody Isotype
IgG2a, k
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Preservative
0.09% Sodium azide
Concentration
0.5 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 300-465

Target

Full Name
RIOX2
Introduction
MINA is a c-Myc target gene that may play a role in cell proliferation or regulation of cell growth.
Entrez Gene ID
84864
UniProt ID
Q8IUF8
Alternative Names
Ribosomal Oxygenase 2; Bifunctional Lysine-Specific Demethylase And Histidyl-Hydroxylase MINA; 0S Ribosomal Protein L27a Histidine Hydroxylase; Histone Lysine Demethylase MINA; MYC Induced Nuclear Antigen; Ribosomal Oxygenase MINA; Nucleolar Protein 52; MINA53; MINA; MDIG
Function
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.
Biological Process
Histone H3-K36 demethylation Source: GO_Central
Histone H3-K4 demethylation Source: GO_Central
Ribosome biogenesis Source: UniProtKB-KW
Cellular Location
Nucleus
Nucleolus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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