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Rat Anti-RIOX2 Recombinant Antibody (CBFYM-3088) (CBMAB-M3284-FY)

This product is rat antibody that recognizes RIOX2. The antibody CBFYM-3088 can be used for immunoassay techniques such as: WB.
See all RIOX2 antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBFYM-3088
Application
WB

Basic Information

Immunogen
Recombinant protein corresponding to mouse MINA
Specificity
Mouse
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Lyophilized
Buffer
PBS
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
RIOX2
Introduction
SETDB2 and RIOX2 might be involved in renal tumorigenesis and RCC progression, especially in metastatic spread.
Entrez Gene ID
67014
UniProt ID
Q8CD15
Alternative Names
Mina; AI449204; 1810047J07Rik; 2410057H13Rik; 3830408E23Rik
Function
Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.
Biological Process
Histone H3-K36 demethylation Source: GO_Central
Histone H3-K4 demethylation Source: GO_Central
Ribosome biogenesis Source: UniProtKB-KW
Cellular Location
Nucleus
Nucleolus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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