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Rat Anti-RLN1 Recombinant Antibody (361505) (CBMAB-R2807-CN)

This product is a Rat antibody that recognizes RLN1. The antibody 361505 can be used for immunoassay techniques such as: WB.
See all RLN1 antibodies

Summary

Host Animal
Rat
Specificity
Human
Clone
361505
Antibody Isotype
IgG2a
Application
WB

Basic Information

Immunogen
E. coli-derived recombinant human Relaxin-1, Lys26-Cys185, Accession # P04808
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
LYOPH
Buffer
PBS, Trehalose
Concentration
LYOPH

Target

Full Name
Relaxin 1
Introduction
Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. [provided by RefSeq, Jan 2013]
Entrez Gene ID
6013
UniProt ID
P04808
Alternative Names
Relaxin 1; Prorelaxin H1; Preprorelaxin H1; Relaxin 1 (H1); BA12D24.3.1; BA12D24.3.2; H1RLX; RLXH1; H1;
Function
Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
Biological Process
Biological Process female pregnancy1 PublicationNAS:ProtInc
Biological Process signal transduction1 PublicationNAS:ProtInc
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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