RLN1

Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In humans there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3, where RLN1 and RLN2 share high sequence homology. The protein encoded by this gene is synthesized as a single-chain polypeptide but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. [provided by RefSeq, Jan 2013]
Full Name
Relaxin 1
Function
Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
Biological Process
Biological Process female pregnancy1 PublicationNAS:ProtInc
Biological Process signal transduction1 PublicationNAS:ProtInc
Cellular Location
Secreted
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Anti-RLN1 antibodies

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Mouse Anti-RLN1 Recombinant Antibody (willi) (CBMAB-R2816-CN)

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Target: RLN1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: willi
Application*: E
Datasheet SDS

Rat Anti-RLN1 Recombinant Antibody (MM0525-6L12) (CBMAB-R2815-CN)

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Target: RLN1
Host: Rat
Antibody Isotype: IgG2
Specificity: Human
Clone: MM0525-6L12
Application*: WB, N
Datasheet SDS

Mouse Anti-RLN1 Recombinant Antibody (kurd) (CBMAB-R2814-CN)

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Target: RLN1
Host: Mouse
Specificity: Human
Clone: kurd
Application*: E, F
Datasheet SDS

Rat Anti-RLN1 Recombinant Antibody (8H157) (CBMAB-R2811-CN)

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Target: RLN1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: 8H157
Application*: E, N, WB
Datasheet SDS

Mouse Anti-RLN1 Recombinant Antibody (8H11kurd) (CBMAB-R2810-CN)

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Target: RLN1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 8H11kurd
Application*: E, F
Datasheet SDS

Mouse Anti-RLN1 Recombinant Antibody (6F1willi) (CBMAB-R2809-CN)

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Target: RLN1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6F1willi
Application*: E, F
Datasheet SDS

Rat Anti-RLN1 Recombinant Antibody (361513) (CBMAB-R2808-CN)

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Target: RLN1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: 361513
Application*: WB, N
Datasheet SDS

Rat Anti-RLN1 Recombinant Antibody (361505) (CBMAB-R2807-CN)

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Target: RLN1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: 361505
Application*: WB
Datasheet SDS

Mouse Anti-RLN1 Recombinant Antibody (351713) (CBMAB-R2806-CN)

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Target: RLN1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 351713
Application*: WB
Datasheet SDS

Mouse Anti-RLN1 Recombinant Antibody (1H6) (CBMAB-R2805-CN)

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Target: RLN1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1H6
Application*: E, IP, WB
Datasheet SDS

Rat Anti-RLN1 Recombinant Antibody (14L817) (CBMAB-R2804-CN)

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Target: RLN1
Host: Rat
Antibody Isotype: IgG2
Specificity: Human
Clone: 14L817
Application*: N, WB
Datasheet SDS

Human Recombinant RLN1 protein, His Tag (V2LY-0526-LY6487)

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Target: RLN1
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-185
Tag: His Tag
Datasheet SDS

RLN1 Matched Antibody Pair (1001) (APMAB-1001LY)

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Target: RLN1
Specificity: Human
Datasheet SDS

RLN1 Matched Antibody Pair (1000) (APMAB-1000LY)

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Target: RLN1
Specificity: Human
Datasheet SDS

RLN1 Matched Antibody Pair (999) (APMAB-999LY)

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Target: RLN1
Specificity: Human
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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