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Rat Anti-RLN2 Recombinant Antibody (349102) (CBMAB-R2819-CN)

This product is a Rat antibody that recognizes RLN2. The antibody 349102 can be used for immunoassay techniques such as: WB, Neut.
See all RLN2 antibodies

Summary

Host Animal
Rat
Specificity
Human
Clone
349102
Antibody Isotype
IgG1
Application
WB, Neut

Basic Information

Immunogen
E. coli-derived recombinant human Relaxin-2, Val23-Cys185, Accession # P04090
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
LYOPH
Buffer
PBS, Trehalose
Concentration
LYOPH

Target

Full Name
Relaxin 2
Introduction
This gene encodes a member of the relaxin subfamily and insulin superfamily of peptide hormones. In humans there are three non-allelic relaxin genes. This gene encodes multiple protein isoforms, at least one of which undergoes proteolytic processing. This processing generates relaxin A and B chains that are linked by disulfide bonds to form the mature peptide hormone. This hormone plays a role in the male and female reproductive systems and was initially noted for its role in pregnancy. This protein also plays broader roles in the cardiovascular system, including in the regulation of blood pressure and control of heart rate, and data from animal models shows that this protein may have anti-fibrotic and cardioprotective effects. [provided by RefSeq, Jul 2016]
Entrez Gene ID
6019
UniProt ID
P04090
Alternative Names
Relaxin 2; Relaxin, Ovarian, Of Pregnancy; Prorelaxin H2; Relaxin H2; H2-Preprorelaxin; Relaxin 2 (H2);
Function
Relaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals. May be involved in remodeling of connective tissues during pregnancy, promoting growth of pubic ligaments and ripening of the cervix.
Biological Process
Biological Process female pregnancyManual Assertion Based On ExperimentTAS:ProtInc
Biological Process positive regulation of angiogenesisManual Assertion Based On ExperimentIMP:CACAO
Biological Process positive regulation of gene expressionManual Assertion Based On ExperimentIDA:CACAO
Biological Process regulation of catalytic activityManual Assertion Based On ExperimentIDA:CACAO
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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