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Mouse Anti-RND1 Recombinant Antibody (1C3) (CBMAB-R2874-CN)

This product is a Mouse antibody that recognizes RND1. The antibody 1C3 can be used for immunoassay techniques such as: WB, FC, IF.
See all RND1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1C3
Antibody Isotype
IgG1
Application
WB, FC, IF

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
Rho Family GTPase 1
Introduction
This gene encodes a protein that belongs to the Rho GTPase family. Members of this family regulate the organization of the actin cytoskeleton in response to extracellular growth factors. A similar protein in rat interacts with a microtubule regulator to control axon extension. [provided by RefSeq, Apr 2014]
Entrez Gene ID
27289
UniProt ID
Q92730
Alternative Names
Rho Family GTPase 1; Ras Homolog Gene Family, Member S; RHO6; Rho-Related GTP-Binding Protein Rho6; ARHS; RHOS; Rnd1;
Function
Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments.
Biological Process
Biological Process actin filament organizationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cortical cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process establishment or maintenance of cell polarityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process negative regulation of cell adhesionManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process neuron remodelingManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process regulation of actin cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of cell shapeManual Assertion Based On ExperimentIBA:GO_Central
Biological Process small GTPase mediated signal transductionIEA:InterPro
Cellular Location
Cell membrane
Cytoplasm, cytoskeleton
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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