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Mouse Anti-RND2 Recombinant Antibody (2D12) (CBMAB-R2876-CN)

This product is a Mouse antibody that recognizes RND2. The antibody 2D12 can be used for immunoassay techniques such as: ELISA.
See all RND2 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2D12
Antibody Isotype
IgG2b, κ
Application
ELISA

Basic Information

Immunogen
Full length recombinant corresponding to aa. 1-170 from RND2 (H18096) with GST tag
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
Rho family GTPase 2
Introduction
This gene encodes a member of the Rho GTPase family, whose members play a key role in the regulation of actin cytoskeleton organization in response to extracellular growth factors. This particular family member has been implicated in the regulation of neuronal morphology and endosomal trafficking. The gene localizes to chromosome 17 and is the centromeric neighbor of the breast-ovarian cancer susceptibility gene BRCA1. [provided by RefSeq, Jul 2008]
Entrez Gene ID
8153
UniProt ID
P52198
Alternative Names
Rho Family GTPase 2; Rho-Related GTP-Binding Protein Rho7; Ras Homolog Gene Family, Member N; ARHN; RHO7; Rho-Related GTP-Binding Protein RhoN;
Function
May be specifically involved in neuronal and hepatic functions. Is a C3 toxin-insensitive member of the Rho subfamily (By similarity).
Biological Process
Biological Process actin filament organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process collateral sproutingIEA:Ensembl
Biological Process cortical cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process establishment or maintenance of cell polarityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of collateral sproutingIEA:Ensembl
Biological Process regulation of actin cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of cell shapeManual Assertion Based On ExperimentIBA:GO_Central
Biological Process signal transductionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process small GTPase mediated signal transductionIEA:InterPro
Cellular Location
Cytoplasmic vesicle, secretory vesicle, acrosome membrane
Colocalizes with RACGAP1 in Golgi-derived proacrosomal vesicles and the acrosome.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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