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Mouse Anti-RND3 Recombinant Antibody (11n165) (CBMAB-R2877-CN)

This product is a Mouse antibody that recognizes RND3. The antibody 11n165 can be used for immunoassay techniques such as: WB.
See all RND3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
11n165
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Synthetic RD1 peptide corresponding to aa. 197-207 from RND3 (P61587)
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
LYOPH
Buffer
PBS, Trehalose

Target

Full Name
Rho Family GTPase 3
Introduction
This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
Entrez Gene ID
390
UniProt ID
P61587
Alternative Names
Rho Family GTPase 3; Rho-Related GTP-Binding Protein Rho8; Ras Homolog Gene Family, Member E; Protein MemB; Rho8; RhoE;
Function
Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.
Biological Process
Biological Process actin cytoskeleton organizationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process actin filament organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cortical cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process establishment or maintenance of cell polarityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of actin cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of cell shapeManual Assertion Based On ExperimentIBA:GO_Central
Biological Process small GTPase mediated signal transductionIEA:InterPro
Cellular Location
Golgi apparatus membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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