RND3
This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]
Full Name
Rho Family GTPase 3
Function
Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.
Biological Process
Biological Process actin cytoskeleton organizationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process actin filament organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cortical cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process establishment or maintenance of cell polarityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of actin cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of cell shapeManual Assertion Based On ExperimentIBA:GO_Central
Biological Process small GTPase mediated signal transductionIEA:InterPro
Biological Process actin filament organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell adhesionManual Assertion Based On ExperimentTAS:ProtInc
Biological Process cell migrationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cortical cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process establishment or maintenance of cell polarityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of actin cytoskeleton organizationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of cell shapeManual Assertion Based On ExperimentIBA:GO_Central
Biological Process small GTPase mediated signal transductionIEA:InterPro
Cellular Location
Golgi apparatus membrane
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Anti-RND3 antibodies
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Target: RND3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: TS106
Application*: WB
Target: RND3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBCNR-562
Application*: E, WB, P
Target: RND3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: 687202
Application*: WB
Target: RND3
Host: Mouse
Antibody Isotype: IgG
Specificity: Mouse
Clone: 5H35
Application*: WB
Target: RND3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5C7E8
Application*: E, WB, P, IF, F
Target: RND3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 5C7B6
Application*: E, WB, P, IF, F
Target: RND3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Mouse, Human
Clone: 4
Application*: WB, C, IF
Target: RND3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Pig
Clone: 3H8F9
Application*: E, WB
Target: RND3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1D2
Application*: WB, E, P
Target: RND3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 11n165
Application*: WB
Target: RND3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2436
Application*: IH, IC, F
Target: RND3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2914
Application*: IH, IC, F
Target: RND3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Pig
Clone: CF371
Application*: ELISA, WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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