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Mouse Anti-RNF180 Recombinant Antibody (1C4) (CBMAB-R2968-CN)

This product is a Mouse antibody that recognizes RNF180. The antibody 1C4 can be used for immunoassay techniques such as: ELISA, WB.
See all RNF180 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1C4
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant protein corresponding to aa. 1-101 from human RNF180 (NP_848627) with GST tag
Specificity
Human
Antibody Isotype
IgG2b, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
ring finger protein 180
Introduction
RNF180 (Ring Finger Protein 180) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include ligase activity and ubiquitin conjugating enzyme binding.
Entrez Gene ID
285671
UniProt ID
Q86T96
Alternative Names
Ring Finger Protein 180; RING-Type E3 Ubiquitin Transferase RNF180; RING Finger Protein 180; E3 Ubiquitin-Protein Ligase RNF180; EC 2.3.2.27; RINES;
Function
E3 ubiquitin-protein ligase which promotes polyubiquitination and degradation by the proteasome pathway of ZIC2.
Biological Process
Biological Process adult behaviorIEA:Ensembl
Biological Process norepinephrine metabolic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of proteasomal ubiquitin-dependent protein catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of protein ubiquitinationIEA:Ensembl
Biological Process protein polyubiquitinationIEA:Ensembl
Biological Process regulation of catalytic activityIEA:Ensembl
Biological Process serotonin metabolic processManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Endoplasmic reticulum membrane
Nucleus envelope
Topology
Cytoplasmic: 1-564
Helical: 565-585
Extracellular: 586-592
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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