RNF180

RNF180 (Ring Finger Protein 180) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include ligase activity and ubiquitin conjugating enzyme binding.

Full Name

ring finger protein 180

Function

E3 ubiquitin-protein ligase which promotes polyubiquitination and degradation by the proteasome pathway of ZIC2.

Biological Process

Biological Process adult behaviorIEA:Ensembl
Biological Process norepinephrine metabolic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of proteasomal ubiquitin-dependent protein catabolic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of protein ubiquitinationIEA:Ensembl
Biological Process protein polyubiquitinationIEA:Ensembl
Biological Process regulation of catalytic activityIEA:Ensembl
Biological Process serotonin metabolic processManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Endoplasmic reticulum membrane
Nucleus envelope

Topology

Cytoplasmic: 1-564
Helical: 565-585
Extracellular: 586-592