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Mouse Anti-RNGTT Monoclonal Antibody (CBFYH-3302) (CBMAB-H3794-FY)

This product is mouse antibody that recognizes RNGTT. The antibody CBFYH-3302 can be used for immunoassay techniques such as: WB.
See all RNGTT antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-3302
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Recombinant human protein purified from E.coli
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
HEPES, 0.15M NaCl, 0.01% BSA, 50% glycerol
Preservative
0.03% Sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
RNA Guanylyltransferase And 5'-Phosphatase
Introduction
RNGTT (RNA Guanylyltransferase And 5'-Phosphatase) is a Protein Coding gene. Diseases associated with RNGTT include Lymphomatous Meningitis and Cecum Adenocarcinoma. Among its related pathways are mRNA Splicing - Major Pathway and Gene Expression. Gene Ontology (GO) annotations related to this gene include GTP binding and protein tyrosine phosphatase activity. An important paralog of this gene is DUSP11.
Entrez Gene ID
8732
UniProt ID
O60942
Alternative Names
RNA Guanylyltransferase And 5'-Phosphatase; RNA Guanylyltransferase And 5-Phosphatase; HCAP1; CAP1A; HCE; MRNA-Capping Enzyme; HCAP; HCE1
Function
Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.
Biological Process
Biological Process 7-methylguanosine mRNA cappingManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process protein dephosphorylationIEA:InterPro
Biological Process RNA processingManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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