Mouse Anti-RNGTT Recombinant Antibody (CBFYM-3090) (CBMAB-M3286-FY)

Name: Mouse Anti-RNGTT Recombinant Antibody (CBFYM-3090)
SKU: CBMAB-M3286-FY
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

CBFYM-3090

Application

Immunogen

Recombinant human protein purified from E.coli

Specificity

Human

Antibody Isotype

IgG1, k

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

HEPES, 0.15 M NaCl, 0.01% BSA

Preservative

0.03% Sodium azide

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

RNA Guanylyltransferase And 5'-Phosphatase

Introduction

RNGTT is a Protein Coding gene. Diseases associated with RNGTT include Lymphomatous Meningitis and Cecum Adenocarcinoma. Among its related pathways are mRNA Splicing - Major Pathway and Gene Expression. Gene Ontology annotations related to this gene include GTP binding and protein tyrosine phosphatase activity. An important paralog of this gene is DUSP11.

Entrez Gene ID

8732

UniProt ID

O60942

Alternative Names

RNA Guanylyltransferase And 5'-Phosphatase; RNA Guanylyltransferase And 5-Phosphatase; HCAP1; CAP1A; HCE; MRNA-Capping Enzyme; HCAP; HCE1

Function

Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.

Biological Process

Biological Process 7-methylguanosine mRNA cappingManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process protein dephosphorylationIEA:InterPro
Biological Process RNA processingManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Nucleus

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

Mouse Anti-RNGTT Monoclonal Antibody (CBFYH-3302) (CAT#: CBMAB-H3794-FY)

Mouse Anti-RNGTT Recombinant Antibody (H-3) (CAT#: CBMAB-R3053-CN)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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