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Mouse Anti-ROMO1 Recombinant Antibody (1C7) (CBMAB-R3141-CN)

This product is a Mouse antibody that recognizes ROMO1. The antibody 1C7 can be used for immunoassay techniques such as: WB.
See all ROMO1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1C7
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Full length human recombinant protein of human ROMO1 (NP_542786) produced in HEK293T cell
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.3, 1% BSA, 50% Glycerol
Preservative
0.02% Sodium azide
Concentration
1 mg/mL

Target

Full Name
Reactive Oxygen Species Modulator 1
Introduction
The protein encoded by this gene is a mitochondrial membrane protein that is responsible for increasing the level of reactive oxygen species (ROS) in cells. The protein also has antimicrobial activity against a variety of bacteria by inducing bacterial membrane breakage. [provided by RefSeq, Nov 2014]
Entrez Gene ID
140823
UniProt ID
P60602
Alternative Names
Reactive Oxygen Species Modulator 1; Mitochondrial Targeting GxxxG Motif Protein; Mitochondrial Targeting GXXXG Protein; Epididymis Tissue Protein Li 175; Protein MGR2 Homolog; ROS Modulator 1; Glyrichin;
Function
Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
Biological Process
Biological Process antimicrobial humoral immune response mediated by antimicrobial peptideManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process cellular response to reactive oxygen speciesManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process cytolysis by host of symbiont cellsManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process defense response to bacteriumManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process defense response to Gram-negative bacteriumManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process defense response to Gram-positive bacteriumManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process intracellular protein transport1 PublicationIC:ComplexPortal
Biological Process killing of cells of another organismManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of cell population proliferationManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process positive regulation of reactive oxygen species metabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process protein import into mitochondrial matrixManual Assertion Based On ExperimentIBA:GO_Central
Biological Process protein insertion into mitochondrial inner membraneManual Assertion Based On ExperimentIBA:GO_Central
Biological Process replicative senescenceManual Assertion Based On ExperimentIMP:GO_Central
Cellular Location
Mitochondrion inner membrane
Topology
Helical: 24-44
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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