Mouse Anti-RPIA Recombinant Antibody (D-5) (CBMAB-R3339-CN)

Name: Mouse Anti-RPIA Recombinant Antibody (D-5)
SKU: CBMAB-R3339-CN
Rating: 5 (1 reviews)

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Basic Information

Host Animal

Mouse

Clone

D-5

Application

WB, IP, IF, ELISA

Specificity

Mouse, Rat, Human

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

More Infomation

Target

Full Name

Ribose 5-Phosphate Isomerase A

Introduction

The protein encoded by this gene is an enzyme, which catalyzes the reversible conversion between ribose-5-phosphate and ribulose-5-phosphate in the pentose-phosphate pathway. This gene is highly conserved in most organisms. The enzyme plays an essential role in the carbohydrate metabolism. Mutations in this gene cause ribose 5-phosphate isomerase deficiency. A pseudogene is found on chromosome 18. [provided by RefSeq, Mar 2010]

Entrez Gene ID

Human	22934
Mouse	19895
Rat	362383

UniProt ID

Human	P49247
Mouse	P47968
Rat	D4A7L6

Alternative Names

Ribose 5-Phosphate Isomerase A; Ribose 5-Phosphate Epimerase; Phosphoriboisomerase; EC 5.3.1.6; RPI; Ribose-5-Phosphate Isomerase; RPIAD;

Function

Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate and participates in the first step of the non-oxidative branch of the pentose phosphate pathway.

Biological Process

Biological Process D-ribose metabolic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process pentose-phosphate shuntTAS:Reactome
Biological Process pentose-phosphate shunt, non-oxidative branchManual Assertion Based On ExperimentIBA:GO_Central
Biological Process ribose phosphate metabolic processIEA:Ensembl

Cellular Location

cytosol
intracellular membrane-bounded organelle

Involvement in disease

Ribose 5-phosphate isomerase deficiency (RPIAD):
An autosomal recessive inborn error of polyols metabolism characterized by highly elevated level of ribitol and arabitol in brain and body fluids. Clinical features include leukoencephalopathy, psychomotor retardation from early life, neurologic regression, and a mild sensorimotor neuropathy.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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