Mouse Anti-RPL10L Recombinant Antibody (1E9) (CBMAB-R3348-CN)

Name: Mouse Anti-RPL10L Recombinant Antibody (1E9)
SKU: CBMAB-R3348-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

1E9

Application

ELISA

Immunogen

Partial recombinant protein corresponding to aa. 115-215 from human RPL10L (NP_542784) with GST tag

Specificity

Human

Antibody Isotype

IgG1, κ

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.2

More Infomation

Target

Full Name

ribosomal protein L10-like

Introduction

This gene encodes a protein sharing sequence similarity with ribosomal protein L10. It is not currently known whether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is independent of the ribosome. This gene is intronless. [provided by RefSeq, Jul 2008]

Entrez Gene ID

140801

UniProt ID

Q96L21

Alternative Names

Ribosomal Protein L10 Like; Large Ribosomal Subunit Protein UL16-Like; 0S Ribosomal Protein L10-Like; Ribosomal Protein L10-Like; RPL10_5_1358;

Function

Testis-specific component of the ribosome, which is required for the transition from prophase to metaphase in male meiosis I (By similarity).
Compensates for the inactivated X-linked RPL10 paralog during spermatogenesis (PubMed:12490704).
The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399, PubMed:25901680, PubMed:32669547).
The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules (PubMed:23636399, PubMed:25901680, PubMed:32669547).
The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain (PubMed:23636399, PubMed:25901680, PubMed:32669547).
The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel (PubMed:23636399, PubMed:25901680, PubMed:32669547).

Biological Process

Biological Process cell differentiationIEA:UniProtKB-KW
Biological Process male meiosis IISS:UniProtKB
Biological Process ribosomal large subunit assemblyISS:UniProtKB
Biological Process spermatogenesisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process translationIEA:InterPro

Cellular Location

Cytoplasm

Involvement in disease

Spermatogenic failure 63 (SPGF63):
An autosomal recessive male infertility disorder characterized by severe oligozoospermia and reduced progressive sperm motility.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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