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Mouse Anti-RPL3 Recombinant Antibody (CF373) (CBMAB-FT130LY)

The product is antibody recognizes RPL3 . The antibody CF373 immunoassay techniques such as: ELISA, WB, IHC, IF.
See all RPL3 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CF373
Antibody Isotype
IgG1
Application
ELISA, WB, IHC, IF

Basic Information

Immunogen
ribosomal protein L3
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
50% glycerol
Preservative
0.02% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Ribosomal Protein L3
Introduction
Ribosomes, the complexes that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L3P family of ribosomal proteins and it is located in the cytoplasm. The protein can bind to the HIV-1 TAR mRNA, and it has been suggested that the protein contributes to tat-mediated transactivation. This gene is co-transcribed with several small nucleolar RNA genes, which are located in several of this gene's introns. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Entrez Gene ID
6122
UniProt ID
P39023
Function
Component of the large ribosomal subunit (PubMed:12962325, PubMed:23636399, PubMed:32669547).
The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:12962325, PubMed:23636399, PubMed:32669547).
Biological Process
Biological Process cellular response to interleukin-4IEA:Ensembl
Biological Process cytoplasmic translation1 PublicationIC:FlyBase
Biological Process translationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus, nucleolus
Cytoplasm
PTM
Constitutively monomethylated at His-245 by METTL18 (PubMed:23349634, PubMed:33693809).
Regulates the function of RPL3 in the dynamics of pre-rRNA processing, ribosome biogenesis, and translation (PubMed:33693809).
It is not required for incorporation of RPL3 into ribosomes (PubMed:33693809).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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