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Mouse Anti-RPLP0 Recombinant Antibody (1B4) (CBMAB-R3403-CN)

This product is a Mouse antibody that recognizes RPLP0. The antibody 1B4 can be used for immunoassay techniques such as: ELISA, WB.
See all RPLP0 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1B4
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Full length recombinant corresponding to aa. 1-318 from human RPLP0 (H15173) with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
ribosomal protein, large, P0
Introduction
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Entrez Gene ID
6175
UniProt ID
P05388
Alternative Names
Ribosomal Protein Lateral Stalk Subunit P0; Large Ribosomal Subunit Protein UL10; Neutral Ribosomal Phosphoprotein P0; Ribosomal Protein, Large, P0; 0S Ribosomal Protein L10E; Acidic Ribosomal Phosphoprotein P0; 0S Acidic Ribosomal Protein P0;
Function
Ribosomal protein P0 is the functional equivalent of E.coli protein L10.
Biological Process
Biological Process cellular response to cAMPIEA:Ensembl
Biological Process cellular response to interleukin-4IEA:Ensembl
Biological Process cellular response to phorbol 13-acetate 12-myristateIEA:Ensembl
Biological Process cellular response to Thyroid stimulating hormoneIEA:Ensembl
Biological Process cytoplasmic translationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process lactationIEA:Ensembl
Biological Process response to selenium ionIEA:Ensembl
Biological Process ribosomal large subunit assemblyManual Assertion Based On ExperimentIBA:GO_Central
Biological Process translation1 PublicationNAS:UniProtKB
Cellular Location
Nucleus
Cytoplasm
Localized in cytoplasmic mRNP granules containing untranslated mRNAs (PubMed:19188445, PubMed:17289661).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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