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Mouse Anti-RPP40 Recombinant Antibody (1G8) (CBMAB-R3432-CN)

This product is a Mouse antibody that recognizes RPP40. The antibody 1G8 can be used for immunoassay techniques such as: ELISA, WB.
See all RPP40 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
1G8
Antibody Isotype
IgG2b, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa. 295-363 from human RPP40 (NP_006629) with GST tag
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2

Target

Full Name
ribonuclease P/MRP 40kDa subunit
Entrez Gene ID
10799
UniProt ID
O75818
Alternative Names
Ribonuclease P/MRP Subunit P40; Ribonuclease P/MRP 40kDa Subunit; RNaseP Protein P40; RNase P Subunit 1; Ribonuclease P1; EC 3.1.26.5; RNASEP1;
Function
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:9630247, PubMed:30454648).
Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465).
Biological Process
Biological Process endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)Manual Assertion Based On ExperimentIBA:GO_Central
Biological Process endonucleolytic cleavage involved in tRNA processingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process tRNA 5'-leader removalManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Nucleus, nucleolus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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