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RPP40

Full Name

ribonuclease P/MRP 40kDa subunit

Function

Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:9630247, PubMed:30454648).
Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465).

Biological Process

Biological Process endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)Manual Assertion Based On ExperimentIBA:GO_Central
Biological Process endonucleolytic cleavage involved in tRNA processingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process tRNA 5'-leader removalManual Assertion Based On ExperimentIDA:UniProtKB

Cellular Location

Nucleus, nucleolus

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Anti-RPP40 antibodies

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Mouse Anti-RPP40 Recombinant Antibody (G-4) (CBMAB-R3434-CN)

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Target: RPP40

Host: Mouse

Specificity: Human

Clone: G-4

Application*: WB, IP, IF, E

Mouse Anti-RPP40 Recombinant Antibody (CBCNR-733) (CBMAB-R3433-CN)

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Target: RPP40

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBCNR-733

Application*: E

Mouse Anti-RPP40 Recombinant Antibody (1G8) (CBMAB-R3432-CN)

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Target: RPP40

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 1G8

Application*: E, WB

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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