Mouse Anti-RPS7 Recombinant Antibody (CBCNR-786) (CBMAB-R3596-CN)
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Basic Information
Formulations & Storage [For reference only, actual COA shall prevail!]
Target
Biological Process negative regulation of ubiquitin protein ligase activityManual Assertion Based On ExperimentIDA:CAFA
Biological Process negative regulation of ubiquitin-dependent protein catabolic processManual Assertion Based On ExperimentIDA:CAFA
Biological Process neural crest cell differentiationIEA:Ensembl
Biological Process neural tube closureIEA:Ensembl
Biological Process positive regulation of gene expressionManual Assertion Based On ExperimentIMP:CAFA
Biological Process positive regulation of intrinsic apoptotic signaling pathway by p53 class mediatorManual Assertion Based On ExperimentIMP:CAFA
Biological Process protein stabilizationManual Assertion Based On ExperimentIMP:CAFA
Biological Process ribosomal small subunit biogenesisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process rRNA processingManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process translation1 PublicationNAS:UniProtKB
Cytoplasm
Nucleus
Although RPS7 is functional within the cytoplasm, the assembly of ribosomal subunits occurs in the nucleus. RPS7 nuclear import is mediated by IPO5/RanBP5, IPO7/RanBP7, KPNB1/importin-beta or TPNO1/Trn (PubMed:9687515).
Colocalizes with NEK6 in the centrosome (PubMed:20873783).
A form of Diamond-Blackfan anemia, a congenital non-regenerative hypoplastic anemia that usually presents early in infancy. Diamond-Blackfan anemia is characterized by a moderate to severe macrocytic anemia, erythroblastopenia, and an increased risk of malignancy. 30 to 40% of Diamond-Blackfan anemia patients present with short stature and congenital anomalies, the most frequent being craniofacial (Pierre-Robin syndrome and cleft palate), thumb and urogenital anomalies.
Ubiquitinated. Deubiquitinated by DESI2, leading to its stabilization.
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Please try the standard protocols which include: protocols, troubleshooting and guide.
Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols
Custom Antibody Labeling
We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).
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