Mouse Anti-RRM1 Recombinant Antibody (5G5) (CBMAB-R3676-CN)

Name: Mouse Anti-RRM1 Recombinant Antibody (5G5)
SKU: CBMAB-R3676-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

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Basic Information

Host Animal

Mouse

Clone

5G5

Application

WB, IHC-P

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

More Infomation

Target

Full Name

Ribonucleotide Reductase Catalytic Subunit M1

Introduction

This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

Entrez Gene ID

6240

UniProt ID

P23921

Alternative Names

Ribonucleotide Reductase Catalytic Subunit M1; Ribonucleoside-Diphosphate Reductase Subunit M1; Ribonucleotide Reductase M1 Polypeptide; EC 1.17.4.1; RR1; Ribonucleoside-Diphosphate Reductase Large Subunit;

Function

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

Biological Process

Biological Process 2'-deoxyribonucleotide biosynthetic processManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process deoxyribonucleotide biosynthetic processISS:UniProtKB
Biological Process DNA repairManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process DNA synthesis involved in DNA repair1 PublicationIC:ComplexPortal
Biological Process mitochondrial DNA replicationManual Assertion Based On ExperimentIMP:ComplexPortal
Biological Process positive regulation of G0 to G1 transitionManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process positive regulation of G1/S transition of mitotic cell cycleManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process positive regulation of G2/M transition of mitotic cell cycleManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process protein heterotetramerizationIEA:Ensembl
Biological Process ribonucleoside diphosphate metabolic processManual Assertion Based On ExperimentIDA:ComplexPortal

Cellular Location

Cytoplasm

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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