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Rabbit Anti-RRM1 Recombinant Antibody (CBCNR-803) (CBMAB-R3680-CN)

This product is a Rabbit antibody that recognizes RRM1. The antibody CBCNR-803 can be used for immunoassay techniques such as: WB, IP, IHC-P, IF.
See all RRM1 antibodies

Summary

Host Animal
Rabbit
Specificity
Mouse, Rat, Human
Clone
CBCNR-803
Antibody Isotype
IgG
Application
WB, IP, IHC-P, IF

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
Ribonucleotide Reductase Catalytic Subunit M1
Introduction
This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Entrez Gene ID
Human6240
Mouse20133
Rat685579
UniProt ID
HumanP23921
MouseP07742
RatQ5U2Q5
Alternative Names
Ribonucleotide Reductase Catalytic Subunit M1; Ribonucleoside-Diphosphate Reductase Subunit M1; Ribonucleotide Reductase M1 Polypeptide; EC 1.17.4.1; RR1; Ribonucleoside-Diphosphate Reductase Large Subunit;
Function
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
Biological Process
Biological Process 2'-deoxyribonucleotide biosynthetic processManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process deoxyribonucleotide biosynthetic processISS:UniProtKB
Biological Process DNA repairManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process DNA synthesis involved in DNA repair1 PublicationIC:ComplexPortal
Biological Process mitochondrial DNA replicationManual Assertion Based On ExperimentIMP:ComplexPortal
Biological Process positive regulation of G0 to G1 transitionManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process positive regulation of G1/S transition of mitotic cell cycleManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process positive regulation of G2/M transition of mitotic cell cycleManual Assertion Based On ExperimentIDA:ComplexPortal
Biological Process protein heterotetramerizationIEA:Ensembl
Biological Process ribonucleoside diphosphate metabolic processManual Assertion Based On ExperimentIDA:ComplexPortal
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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