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Mouse Anti-RSPH1 Recombinant Antibody (CBYJT-1647) (CBMAB-T0693-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to RSPH1 (Radial Spoke Head 1 Homolog). The antibody can be used for immunoassay techniques, such as ELISA, WB.
See all RSPH1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-1647
Antibody Isotype
IgG2a, κ
Application
ELISA, WB

Basic Information

Immunogen
Partial recombinant corresponding to aa200-310 from human TSGA2 (NP_543136) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 200-310

Target

Full Name
Radial Spoke Head 1 Homolog
Introduction
RSPH1 is a male meiotic metaphase chromosome-associated acidic protein. RSPH1 is expressed in tissues with motile cilia or flagella, including the trachea, lungs, airway brushings, and testes. Mutations in RSPH1 result in primary ciliary dyskinesia-24.
Entrez Gene ID
89765
UniProt ID
Q8WYR4
Alternative Names
Radial Spoke Head 1 Homolog; Meichroacidin; Male Meiotic Metaphase Chromosome-Associated Acidic Protein; Cancer/Testis Antigen 79; TSGA2; CT79; TSA2; Radial Spoke Head 1 Homolog (Chlamydomonas)
Function
May play an important role in male meiosis (By similarity).
It is necessary for proper building of the axonemal central pair and radial spokes.
Biological Process
Biological Process axoneme assemblyManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process meiotic cell cycleIEA:UniProtKB-KW
Biological Process spermatid developmentManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
Cell projection, cilium
Cytoplasmic in late spermatocytes, secondary spermatocytes and round spermatids. Gathered around metaphase chromosomes during meiotic divisions (By similarity).
Involvement in disease
Ciliary dyskinesia, primary, 24 (CILD24):
A disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia. Situs inversus is not observed in CILD24 patients.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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