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Mouse Anti-RUFY1 Recombinant Antibody (A-4) (CBMAB-R3829-CN)

This product is a Mouse antibody that recognizes RUFY1. The antibody A-4 can be used for immunoassay techniques such as: WB, IP, IF, ELISA.
See all RUFY1 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
A-4
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Human
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
RUN and FYVE domain containing 1
Introduction
This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Entrez Gene ID
80230
UniProt ID
Q96T51
Alternative Names
RUN And FYVE Domain Containing 1; Zinc Finger FYVE Domain-Containing Protein 12; Rab4-Interacting Protein; FYVE-Finger Protein EIP1; La-Binding Protein 1; ZFYVE12; RABIP4; RUN And FYVE Domain-Containing Protein 1;
Function
Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking.
Biological Process
Biological Process endocytosisIEA:UniProtKB-KW
Biological Process protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of endocytosisManual Assertion Based On ExperimentIPI:UniProtKB
Biological Process small GTPase mediated signal transductionIEA:Ensembl
Cellular Location
Cytoplasm
Early endosome membrane
PTM
Phosphorylation on Tyr-389 and/or Tyr-400 is required for interaction with BMX and endosomal targeting.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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