Mouse Anti-RUFY1 Recombinant Antibody (A-4) (CBMAB-R3829-CN)

Name: Mouse Anti-RUFY1 Recombinant Antibody (A-4)
SKU: CBMAB-R3829-CN
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

A-4

Application

WB, IP, IF, ELISA

Specificity

Human

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

More Infomation

Target

Full Name

RUN and FYVE domain containing 1

Introduction

This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Entrez Gene ID

80230

UniProt ID

Q96T51

Alternative Names

RUN And FYVE Domain Containing 1; Zinc Finger FYVE Domain-Containing Protein 12; Rab4-Interacting Protein; FYVE-Finger Protein EIP1; La-Binding Protein 1; ZFYVE12; RABIP4; RUN And FYVE Domain-Containing Protein 1;

Function

Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in early endosomal trafficking.

Biological Process

Biological Process endocytosisIEA:UniProtKB-KW
Biological Process protein transportManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of endocytosisManual Assertion Based On ExperimentIPI:UniProtKB
Biological Process small GTPase mediated signal transductionIEA:Ensembl

Cellular Location

Cytoplasm
Early endosome membrane

PTM

Phosphorylation on Tyr-389 and/or Tyr-400 is required for interaction with BMX and endosomal targeting.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Related Products

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Mouse Anti-RUFY1 Recombinant Antibody (CBXS-3260) (CAT#: CBMAB-S6001-CQ)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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