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Mouse Anti-RXFP3 Recombinant Antibody (2H10) (CBMAB-R3932-CN)

This product is a Mouse antibody that recognizes RXFP3. The antibody 2H10 can be used for immunoassay techniques such as: ELISA, IHC.
See all RXFP3 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Rat
Clone
2H10
Antibody Isotype
IgG2b, κ
Application
ELISA, IHC

Basic Information

Immunogen
Partial peptide of Human RXFP3 (3rd extracellular domain)
Specificity
Human, Rat
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
0.25 mg/mL

Target

Full Name
Relaxin/Insulin Like Family Peptide Receptor 3
Introduction
RXFP3 (Relaxin/Insulin Like Family Peptide Receptor 3) is a Protein Coding gene. Among its related pathways are Peptide ligand-binding receptors and Relaxin signaling pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and G-protein coupled peptide receptor activity. An important paralog of this gene is RXFP4.
Entrez Gene ID
Human51289
Rat294807
UniProt ID
HumanQ9NSD7
RatQ5Y986
Alternative Names
Relaxin/Insulin Like Family Peptide Receptor 3; Relaxin Family Peptide Receptor 3; G-Protein Coupled Receptor GPCR135; G Protein-Coupled Receptor SALPR; RLN3 Receptor 1; RLN3R1; SALPR; Somatostatin- And Angiotensin-Like Peptide Receptor;
Function
Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.
Biological Process
Biological Process G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Biological Process neuropeptide signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of cytokinesisManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cell membrane
Topology
Extracellular: 1-81
Helical: 82-102
Cytoplasmic: 103-119
Helical: 120-140
Extracellular: 141-156
Helical: 157-177
Cytoplasmic: 178-215
Helical: 216-236
Extracellular: 237-270
Helical: 271-291
Cytoplasmic: 292-329
Helical: 330-350
Extracellular: 330-350
Helical: 357-377
Cytoplasmic: 378-469
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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