RXFP3

RXFP3 (Relaxin/Insulin Like Family Peptide Receptor 3) is a Protein Coding gene. Among its related pathways are Peptide ligand-binding receptors and Relaxin signaling pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and G-protein coupled peptide receptor activity. An important paralog of this gene is RXFP4.

Full Name

Relaxin/Insulin Like Family Peptide Receptor 3

Function

Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.

Biological Process

Biological Process G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Biological Process neuropeptide signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of cytokinesisManual Assertion Based On ExperimentIMP:UniProtKB

Cellular Location

Cell membrane

Topology

Extracellular: 1-81
Helical: 82-102
Cytoplasmic: 103-119
Helical: 120-140
Extracellular: 141-156
Helical: 157-177
Cytoplasmic: 178-215
Helical: 216-236
Extracellular: 237-270
Helical: 271-291
Cytoplasmic: 292-329
Helical: 330-350
Extracellular: 330-350
Helical: 357-377
Cytoplasmic: 378-469

Anti-RXFP3 antibodies

Mouse Anti-RXFP3 Recombinant Antibody (2H10) (CBMAB-R3932-CN)

Datasheet

SDS

Target: RXFP3

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human, Rat

Clone: 2H10

Application*: E, IH

Mouse Anti-RXFP3 Recombinant Antibody (1F10) (CBMAB-A7622-LY)

Datasheet

SDS

Target: RXFP3

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 1F10

Application*: WB, E

Mouse Anti-RXFP3 Recombinant Antibody (1F10) (CBMAB-1791-CN)

Datasheet

SDS

Target: RXFP3

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 1F10

Application*: WB, E

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)