RXFP3
RXFP3 (Relaxin/Insulin Like Family Peptide Receptor 3) is a Protein Coding gene. Among its related pathways are Peptide ligand-binding receptors and Relaxin signaling pathway. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and G-protein coupled peptide receptor activity. An important paralog of this gene is RXFP4.
Full Name
Relaxin/Insulin Like Family Peptide Receptor 3
Function
Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation.
Biological Process
Biological Process G protein-coupled receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Biological Process neuropeptide signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of cytokinesisManual Assertion Based On ExperimentIMP:UniProtKB
Biological Process neuropeptide signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of cytokinesisManual Assertion Based On ExperimentIMP:UniProtKB
Cellular Location
Cell membrane
Topology
Extracellular: 1-81
Helical: 82-102
Cytoplasmic: 103-119
Helical: 120-140
Extracellular: 141-156
Helical: 157-177
Cytoplasmic: 178-215
Helical: 216-236
Extracellular: 237-270
Helical: 271-291
Cytoplasmic: 292-329
Helical: 330-350
Extracellular: 330-350
Helical: 357-377
Cytoplasmic: 378-469
Helical: 82-102
Cytoplasmic: 103-119
Helical: 120-140
Extracellular: 141-156
Helical: 157-177
Cytoplasmic: 178-215
Helical: 216-236
Extracellular: 237-270
Helical: 271-291
Cytoplasmic: 292-329
Helical: 330-350
Extracellular: 330-350
Helical: 357-377
Cytoplasmic: 378-469
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Anti-RXFP3 antibodies
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Target: RXFP3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1F10
Application*: WB, E
Target: RXFP3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Rat
Clone: 2H10
Application*: E, IH
Target: RXFP3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1F10
Application*: WB, E
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(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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