Mouse Anti-RXRB Recombinant Antibody (11-13) (CBMAB-R3953-CN)

Name: Mouse Anti-RXRB Recombinant Antibody (11-13)
SKU: CBMAB-R3953-CN
Rating: 5 (1 reviews)

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Datasheet

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Basic Information

Host Animal

Mouse

Clone

11-13

Application

WB, IP, IF, ELISA

Specificity

Human

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

More Infomation

Target

Full Name

RXRB

Introduction

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). The encoded protein forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Entrez Gene ID

6257

UniProt ID

P28702

Alternative Names

Retinoid X Receptor Beta; Nuclear Receptor Subfamily 2 Group B Member 2; NR2B2; MHC Class I Promoter Binding Protein; Retinoic Acid Receptor RXR-Beta; Retinoid X Receptor, Beta; H-2RIIBP; DAUDI6; RCoR-1;

Function

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE).

Biological Process

Biological Process anatomical structure developmentManual Assertion Based On ExperimentIBA:GO_Central
Biological Process cell differentiationManual Assertion Based On ExperimentIBA:GO_Central
Biological Process positive regulation of bone mineralization1 PublicationIC:ComplexPortal
Biological Process positive regulation of DNA-templated transcriptionManual Assertion Based On ExperimentIDA:GO_Central
Biological Process positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:NTNU_SB
Biological Process regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Biological Process response to retinoic acidManual Assertion Based On ExperimentIBA:GO_Central
Biological Process retinoic acid receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Nucleus
Cytoplasm

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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